Rebalancing Heart Failure
Introducing SAVM: Splanchnic Ablation for Volume Management
Treating a root cause of Heart Failure, rather than just the signs and symptoms.
Using the Axon™ Ablation System, SAVM unilaterally ablates the Greater Splanchnic Nerve to reduce sympathetic activity with the goal of restoring volume balance, increasing cardiac functional capacity and improving symptoms for heart failure patients with preserved ejection fraction (HFpEF).
The Problem
A hallmark of heart failure progression is an overactive sympathetic nervous system (SNS). The SAVM procedure aims to reduce sympathetic nerve activity and address a root cause of heart failure.
The SAVM Procedure
During the implant-free procedure, the Axon Ablation Catheter is inserted into the femoral vein, navigated through the venous system to a target vessel near the right greater splanchnic nerve.
Once there, the vessel is treated with targeted ablation therapy to block nerve signals, reducing sympathetic activity and restoring volume balance in the body.
The outpatient procedure can typically be performed in under an hour.
Minimally invasive, implant-free procedure
Designed to reverse heart congestion
Safe, innovative solution
Clinical Experience
Rebalance-HF roll-in cohort, 6-month results, presented at THT 2023 in Boston, MA.
-6.1
mmHg
+19
in KCCQ
+76
meters
1 Fudim M et al. J Am Heart Assoc. 2017 Aug 17;6(8)
